• presentation-present-talk-public-speaking HBI Seminars minus-thin plus-thin

    HBI Seminar Series

    HBI was launched in Nov 2019. As we entered 2020 and found ourselves WFH, we launched the HBI Seminar Series in a virtual format. Every fortnight, 2 speakers spoke for 20min each. Our original aim was to learn more about the research going on within HBI to increase collaboration. However, it quickly became apparent that our work is influenced by multiple local, national and international partners. Thus the series quickly expanded. The seminar series continues with a face to face and virtual option.

    Please join us!

    • 13 September 2021 - Dr Michaela Johnson minus-thick plus-thick

       

      'Exploring olfactory dysfunction and lysosomal mutations in the prodromal α-synuclein preformed fibrils mouse model.'

      13
      SEPT 21

      Dr Michaela Johnson.jpgDr Michaela Johnson completed a PhD in Medical Science at the University of South Australia in 2018, with her research focused on establishing an early (prodromal) model of Parkinson’s disease, using the neurotoxin rotenone. Upon conferral of her PhD, Michaela was appointed to a highly competitive postdoctoral fellow position working with internationally renowned Parkinson’s disease expert Patrik Brundin, and his laboratory team at the Van Andel Institute in Michigan, USA. While working at the Van Andel Institute, Michaela’s research focused on using the α-synuclein preformed fibrils model of Parkinson’s Disease to investigate how different environmental triggers and genetic mutations affect the cell-to-cell transfer of pathology.

      Date: Monday 13 September, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

      Zoom link
      Password: 745694

      Download the presentation

    • 30 August 2021 - Dr Joanne Davidson & A/Professor Kathy Gatford minus-thick plus-thick

       

      'Should we treat mild perinatal hypoxic-ischemic brain injury?'

      30
      AUG 21

      Dr Joanne Davidson

      Dr Davidson is a senior research fellow in the fetal physiology and neuroscience group at The University of Auckland, New Zealand. The overarching goal of her research is to understand the mechanisms of perinatal brain injury with a focus on the development of new treatment strategies. Her research interests include connexin hemichannel biology, inflammation, optimisation of therapeutic hypothermia, the use of recombinant erythropoietin and human amnion epithelial cells as neuroprotective treatments and the development of treatment strategies for mild hypoxic-ischemic encephalopathy.

      'Understanding and alleviating the impacts of maternal asthma'

      Associate Professor Kathy GatfordKathy is a group leader in the Robinson Research Institute, and a teaching-research academic in the newly formed School of Biomedicine, at the University of Adelaide. She has broad research interests in normal and complicated pregnancy, how these impact the health of progeny, and interventions to improve maternal and progeny health. Asthma affects the pregnancies of ~40000 Australian women each year, and we are using a variety of experimental approaches to not only understand how asthma affects the mother and her infant, but also to answer the question of whether pregnancy also affects asthma progression.

      Date: Monday 30 August, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

    • 2 August 2021 - Dr Nadia Corsini minus-thick plus-thick

       

      'Consumer engagement in research - where to start'

      1
      AUG 21

      Dr Nadia CorsiniDr Nadia Corsini is a Senior Research Fellow at the Rosemary Bryant AO Research Centre.

      Nadia is an experienced behavioural scientist who has worked extensively with industry, government and nongovernment organisations on research and evaluation projects focused on promoting health and wellbeing and supporting people recovering from illness. Nadia’s primary research interests centre around improving quality of life for people affected by cancer. She is passionate about consumer engagement and has been actively engaged with the Community and Consumer Action Group at Health Translation SA.

      In this presentation you will learn about how to get started with engaging consumers in your research, how to do this well, and what support is available.

      Date: Monday 1 August, 1:00-2:00pm​
      Location: Zoom only

    • 19 July 2021 - Dr Claire Jones minus-thick plus-thick

       

      'Biomechanics in neurotrauma research'

      19
      JUL 21

      Dr Claire JonesDr Claire Jones is a mechanical engineer who studies the biomechanics of the musculoskeletal and nervous systems in normal, diseased and injured states. A better understanding of such biomechanics contributes to improved disease and injury prevention strategies, diagnostic tests and conservative and surgical management. One focus of Claire’s research is the trauma that results from sudden injury to the head or spine, such as concussions, traumatic brain injuries (TBI), skull fractures, spinal column fractures, and spinal cord injuries (SCI).  In this presentation, she will discuss pre-clinical and cadaver models that she develops to study injury mechanisms, outcomes, and interventions.

      Claire is a Senior Research Fellow, jointly appointed in the Adelaide Medical School and School of Mechanical Engineering, at The University of Adelaide. She leads the Adelaide Spinal Research Group (ASRG), within the Centre for Orthopaedics & Trauma Research. Her team currently comprises six PhD students, a postdoctoral researcher and a research assistant, with backgrounds in medical sciences and engineering. ASRG research is currently supported by the Australian Research Council (Discovery Project), Perpetual Impact Philanthropy (Kevin Darrell Clarke Endowment), Neurosurgical Research Foundation, The Hospital Research Foundation, and North American Spine Society.

      Date: Monday 19 July, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

    • 21 June 2021 - Linda Rozenberga & Jie (Juliet) Yan minus-thick plus-thick

       

      'Metal Organic Framework based fibre-optic sensors.'

      21
      JUN 21

      Linda Rozenberga

      In the mineral leaching process, there are several factors that have a substantial effect on the reaction kinetics and yield, amongst them the reaction participating ion concentration. Currently, there are a limited number of analytical techniques that allow fast and accurate Fe3+ ion concentration measurements. The aim of this project is to develop a sensitive, selective and fast responding optical fibre based ferric ion sensor using a metal organic framework coating as the spectroscopic probe.

      'Development of new injectable biomaterials for the delivery of cells and therapeutic agents'

      Jie (Juliet) YanJuliet is a PhD candidate at UniSA Clinical and Health Sciences. Her research focuses on the development of injectable biomaterials for the delivery of cells and therapeutic agents, which aims to identify new polymeric biomaterials to provide novel systems for tissue engineering and controlled delivery of adoptive cell therapies.

      Date: Monday 21 June, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

    • 7 June 2021 - Dr Lin Kooi Ong minus-thick plus-thick

      'Secondary neurodegeneration after stroke: Neuropathological changes and potential therapeutic targets.'

      7
      JUNE 21

      Dr Lin Kooi OngLin Ong is a teaching & research academic at the School of Pharmacy, Monash University Malaysia. He is an emerging researcher in translational stroke research. His research directly addresses two of the most challenging problems in stroke and cerebrovascular conditions:

      1. how to prevent widespread neuronal cell death after brain injury/ischemia, and
      2. how to promote brain recovery to yield the greatest possible functional outcome.

      His work to date has provided direct evidence that stroke initiates delayed tissue loss in remote brain regions that are functionally connected to the primary infarction site. He further demonstrated the association between stroke induced secondary neurodegeneration and cognitive impairment. Critically, he has shown the modulation of brain repair mechanisms using pharmacological and non-pharmacological approaches can promote stroke recovery.

      Date: Monday 7 June, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

      Download the presentation

    • 24 May 2021 - A/Prof Maurizio Costabile & A/Prof Sally Plush minus-thick plus-thick

       

      'Animal Ethics.'

      24
      MAY 21

      Associate Professor Maurizio Costabile

      Maurizio is a teaching focussed academic in Clinical and Health Sciences. He Chairs the Animal Ethics Committee and is currently Dean of Research at Education Futures. His educational research focusses on innovative approaches to enhance student learning. He has successfully applied interactive simulations to enhance student learning in lectures and practicals.

      Maurizio is also a senior member of the Molecular Signalling laboratory, which studies the enzyme, sphingosine kinase.

      In this seminar, Maurizio will provide an overview of how the AEC reviews an application and, he will highlight common areas of an application which can delay and/or lead to a rejection.

      'Research Integrity'

      Associate Professor Sally PlushSally is a research academic at UniSA Clinical and Health Sciences. In addition to her research and teaching roles, she is the Academic Integrity Advisor for City East and the Bradley Building. The Australian community expects research to be conducted responsibly, ethically and with integrity and as researchers it is important we know what this looks like and we promote the responsible conduct of research.

      This talk will focus on areas of research integrity and some common ‘mistakes’ that can easily occur.

      Date: Monday 24 May, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

    • 10 May 2021 - Professor Alan Boddy minus-thick plus-thick

       

      'Project-based Higher Degree by Research and Measures of Success.'

      10
      MAY 21

      Professor Alan Boddy

      Alan is Dean of Research and Institute Director, Clinical and Health Sciences. He will be talking about the new Project-based Higher Degree by Research process and the Research and Enterprise Measures of Success.

      Date: Monday 10 May, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

    • 29 March 2021 - Dr Emily Meyer minus-thick plus-thick

       

      'Corticosteroid-binding globulin (CBG): role in cortisol transport and inflammation.'

      29
      MAR 21

      Dr Emily Meyer

      Dr Emily Meyer is an Endocrinologist at the Royal Adelaide and Queen Elizabeth Hospitals. She is completing a PhD in corticosteroid-binding globulin (CBG) in septic shock and was successful in being awarded the AR Clarkson Scholarship, Royal Adelaide Hospital Research Fund.

      CBG is the key transport protein for cortisol and other steroid hormones.It is a non-inhibitory serine protease inhibitor, capable of conformational change from a high cortisol-binding affinity form to a low affinity form upon cleavage of its reactive centre loop by various proteases, such as neutrophil elastase.CBG is naturally designed to optimise the human body’s natural response to inflammation by facilitating maximal cortisol delivery via four key mechanisms: pyrexia, reduced synthesis, neutrophil elastase cleavage and tissue acidosis. Our human studies demonstrate that a lack of targeted delivery of natural cortisol and/or administered hydrocortisone to damaged tissue is due to deficient serum concentrations of CBG, perpetuating organ failure and death in sepsis.
      Pregnancy and the estrogen-based combined oral contraceptive pill increase CBG concentrations threefold through increased hepatic synthesis, placental derived CBG and pregnancy induced changes in glycosylation patterns.Speculatively, increased circulating CBG concentrations in pregnancy may provide an increased reservoir of CBG-bound cortisol to prepare for the risk of puerperal infection or allow for cortisol binding in the face of competition from increased circulating progesterone concentrations.

      Date: Monday 29 March, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

    • 15 March 2021 - Dr Amy Holmes minus-thick plus-thick

       

      'Interactions of nanomaterials with skin and vaginal mucosa.'

      15
      MAR 21

      Dr Amy Holmes

      Amy has just begun her ECR fellowship funded by The Hospital Research Foundation where she is developing novel antiseptic formulations for the treatment of vaginal and perineal tears caused by childbirth. She uses state-of-the-art imaging techniques to study the effects of nanomaterials on biological tissue. She will be discussing how her research on the skin is informing the development of novel formulations for the vaginal mucosa.

      Date: Monday 15 March, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

    • 1 March 2021 - Dr Santosh Adiraju minus-thick plus-thick

       

      'Investigating Cytochrome P450 mediated drug metabolism in patients on extracorporeal life support.'

      1
      MAR 21

      Santosh completed his PhD in 2019 from the University of Queensland. He started working as an early career researcher with A/Prof Cobus Gerber at University of South Australia Clinical & Health Sciences.

      Date: Monday 1 March, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

    • 15 February 2021 - Dr Andrea Stringer minus-thick plus-thick

       

      'Vitamin D: bringing sunshine to the crypts of the intestine.'

      15
      FEB 21

      Dr Andrea Stringer

      Dr Andrea Stringer is Theme Leader for Gut Health and Deputy Director of Health and Biomedical Innovation in UniSA Clinical and Health Sciences.

      She leads research on gut function and gut microbiome, developing strategies for preventing or treating oral and gastrointestinal damage following cancer treatments (mucositis) to reduce the burden of cancer.  Her work involves identifying the mechanisms underpinning the damage that occurs following cancer treatments, with studies investigating the microbiome, inflammatory cytokines, the mucus barrier, and the enteric nervous system.

      She has been involved in multiple pre-clinical investigations evaluating mucositis treatments and their effectiveness in treating cancer treatment-induced mucositis.  Her current work focusses on the role of vitamin D in the intestine, specifically maintaining the microbiome, an anti-inflammatory environment and barrier function.

      Date: Monday 15 February, 11:30-12:30​
      Location: Bradley Building, HB8-18 and Zoom

  • work-meeting-teamwork Symposia minus-thin plus-thin

    HBI Symposia

    HBI is committed to supporting all researchers, but particularly our emerging leaders, in opportunities to share their work. Thus, we regularly hold symposia that give HDRs, ECRs and MCRs the opportunity to showcase their work and to win prizes as voted by the audience. These symposia are held face to face and virtually to promote participation from a broad base.

    • 24 September 2021 - Emerging Researchers Symposium minus-thick plus-thick

      Emerging Researchers Symposium

      24
      SEPT 21

      Location: Bradley Building, HB8-18 and Zoom

      Zoom details: Join the Zoom here Password: 732562

      Time

      Speaker

      Title

      1230

      Introduction - Prof Janna Morrison & Dr Andrea Stringer

       

      Physiology across the lifespan Chaired by A/Prof Paul Anderson 

      1240

      Ms Catherine Dimasi

      Redox ratio in the left ventricle of the growth restricted fetus is linked to cardiac output

      1250

      Ms Kim Gibson

      Adverse events associated with umbilical catheters: a systematic review and meta-analysis

      1300

      Ms Olivia Yea Rin Lee

      Mass spectrometry tissue imaging identifies complex/hybrid-type N-glycans as putative novel cartilage degradation markers for human knee osteoarthritis.

      1310

      Ms Hannah Edwards

      Synthetic oxytocin and mother-infant bonding

      1320

      Dr Nicole Wittwer

      Antibody drug conjugate induces cell death and inti-tumour immunity in mouse models of cancer

      1330

      Dr Ashley Meakin

      Hepatic cytochrome P450 function is altered in a preclinical guinea pig model of NAFLD

      BREAK

       

      Bug, bites and the Big C Chaired by Dr Ash Meakin and A/Prof Rietie Venter

      1400

      Mr Muhammed Awad

      Photoactive nano-fats a new weapon against superbugs!

      1410

      Mr Samuel Nitschke

      Antibacterial coumarin amphiphiles targeting bacterial membranes

      1420

      Ms Kay Myo Min

      Desmoglein-2 promotes an aggressive phenotype of pancreatic cancer: implications for therapeutic intervention

      1430

      Ms Larissa Braz Sousa

      Citizen science and public health: integrating this partnership into mosquito surveillance programs

      1440

      Dr Amy Holmes

      Vaginal mucosa infections: an unmet clinical challenge

      BREAK

       

      People, Places and Passage Chaired by Dr Amy Holmes and A/Prof Michael Wiese

      1500

      Ms Tien Bui

      Assessing understanding and knowledge of psychotropic medication in community mental health consumers.

      1510

      Ms Laura Lunardi

      Effectiveness of patient activation interventions compared with usual care on health-related behavioural outcomes in adults with chronic kidney disease: a systematic review and meta-analysis

      1520

      Ms Ruba Almasr

      The role of silica microporosity on abiraterone acetate solubilization

      1530

      Dr Renly Lim

      Can’t spell “medicine” without “me”: Development of a patient-driven digital tool to report medicine-related side effects

      1540

      Dr Jacinta Johnson

      Administration of buprenorphine long-acting injections by community pharmacists: Addressing access barriers to treatment for opioid addiction.

      1550

      Dr Hayley Schultz

      The impact of caffeine on the renal clearance of calcium

       

      Closing - Dr Andrea Stringer & Prof Janna Morrison

      1600-1700

      NETWORKING

    • 16 April 2021 - HBI Trainee Symposium minus-thick plus-thick

      Trainee Symposium Program

      16
      APRIL 21

      Time

      Speaker

      Title

      1:00-

      1:10pm

      Introduction - Prof Janna Morrison and Dr Andrea Stringer

      1:10-

      1:30pm

      A/Prof Michael Wiese

      Technical speak: LCMS/MS

      1:30-

      1:45pm

      Ms Catherine Dimasi

      Redox ratio in the left ventricle of the growth restricted fetus is linked to cardiac output

      1:45-

      2:05pm

      Dr Ashley Meakin

      Hepatic cytochrome P450 function is altered in a preclinical guinea pig model of NAFLD

      2:05-

      2:15pm

      Break

      2:15-

      2:35pm

      Dr Sheree Bailey

      Technical speak: Flow cytometry

      2:35-

      2:55pm

      A/Prof Paul Anderson

      Technical speak: microCT and bioluminescence

      2:55-

      3:10pm

      Ms Yea Rin Olivia Lee

      Mass spectrometry imaging identifies complex/hybrid-type N-glycans as putative novel cartilage degradation markers for human knee osteoarthritis

      3:10pm

      Close and networking

      Date: Monday 16 April, 13:00-15:10​
      Location: Bradley Building, HB8-18 and Zoom