Bone Growth and Repair Research Group

Bone Growth and Repair

Childhood bone health is critical for ensuring healthy development, and the peak bone mass achieved in adolescence also profoundly influences adult bone health. Bone/cartilage disorders (including osteoporosis, fractures and arthritis) are now major health burdens and identified as a national health research priority area in Australia. The Bone Growth and Repair research group explores the mechanisms and regulation of children's bone growth, bone growth defects, growth plate and bone injury and repair, cancer chemotherapy, and/or ageing-induced bone loss, with the aims of understanding the underlying pathobiology and developing biological treatments that impact on children’s bone growth, bone mass accumulation and adult bone health.

Our Research

Using in vivo, ex vivo and in vitro models and a wide range of histological, cellular and molecular techniques, the group's research activities can be classified into three areas:

  1. Mechanisms of bone growth, regulation of bone mass and early prevention of osteoporosis using natural bioactive nutraceuticals;
  2. Mechanisms for growth plate cartilage and bone injury repair, and development of growth factor and/or stem cell-based therapy for regeneration; and
  3. Pathobiology for and prevention of cancer chemotherapy-induced bone growth arrest, bone loss, and bone marrow adiposity.

Read more about our current research


The Bone Growth and Repair research group enjoys productive relationships with various collaborators, including:

  • Associate Professor Bruce Foster (Women's and Children's Hospital)
  • Professor Peter Howe (University of South Australia & University of Newcastle)
  • Professor Ross McKinnon (Flinders University)
  • Professor Xin-Fu Zhou (University of South Australia)
  • Professor Gordon Howarth (University of Adelaide)
  • Professor Jiake Xu (University of Western Australia)
  • Professor Hong Zhou (University of Sydney)
  • Dr Alessandro Piergentili (University of Camerino, Italy)
  • Professor Dorothy Keefe and Dr Joanne Bowen (Royal Adelaide Hospital and University of Adelaide)
  • Associate Professor Bev Muhlhausler (University of Adelaide)
  • Professor Susanta hui (University of Minnesota, USA)
  • Dr Hamish Wallace (Royal Hospital for Sick Children, Edinburgh, UK)
  • Professor Howard Morris (University of South Australia & IMVS)
  • Professor Keming Chen (Institute of Orthopaedics, Lanzhou, China)
  • Dr Hu Zhang (University of Adelaide)
  • Professor Lin Chen (Daping Hospital Trauma Centre, Chongqing, China)


Attached is a list of selected research publications involving members of the Bone Growth and Repair Research Unit (UniSA researchers are indicated in bold).

Journal Articles, Review Articles and Book Chapters

Contact Us

Media enquiries:
Please visit the Media Centre

All other enquiries:
Professor Cory Xian 
t: +61 8 8302 1944